Exposure to Mitochondrial Genotoxins and Dopaminergic Neurodegeneration in Caenorhabditis elegans

Neurodegeneration has been correlated with mitochondrial DNA (mtDNA) damage and exposure to environmental toxins, but causation is unclear. We investigated the ability of several known environmental genotoxins and neurotoxins to cause mtDNA damage, mtDNA depletion, and neurodegeneration in Caenorhab...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: González-Hunt, Claudia P., Leung, Maxwell C. K., Bodhicharla, Rakesh K., McKeever, Madeline G., Arrant, Andrew E., Margillo, Kathleen M., Ryde, Ian T., Cyr, Derek D., Kosmaczewski, Sara G., Hammarlund, Marc, Meyer, Joel N.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2014
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4259338/
https://ncbi.nlm.nih.gov/pubmed/25486066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0114459
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