Exposure to Mitochondrial Genotoxins and Dopaminergic Neurodegeneration in Caenorhabditis elegans

Neurodegeneration has been correlated with mitochondrial DNA (mtDNA) damage and exposure to environmental toxins, but causation is unclear. We investigated the ability of several known environmental genotoxins and neurotoxins to cause mtDNA damage, mtDNA depletion, and neurodegeneration in Caenorhab...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: González-Hunt, Claudia P., Leung, Maxwell C. K., Bodhicharla, Rakesh K., McKeever, Madeline G., Arrant, Andrew E., Margillo, Kathleen M., Ryde, Ian T., Cyr, Derek D., Kosmaczewski, Sara G., Hammarlund, Marc, Meyer, Joel N.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2014
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4259338/
https://ncbi.nlm.nih.gov/pubmed/25486066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0114459
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