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α4β1 integrin associates with VEGFR2 in CLL cells and contributes to VEGF binding and intracellular signaling

α4β1 integrin and VEGFR2 function as a receptor complex for VEGF in CLL cells. Contribution to VEGF functions in CLL is a novel pathological role for α4β1 integrin in this malignancy.

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Gutiérrez-González, Alejandra, Aguilera-Montilla, Noemí, Ugarte-Berzal, Estefanía, Bailón, Elvira, Cerro-Pardo, Isabel, Sánchez-Maroto, Clara, García-Campillo, Lara, García-Marco, José A., García-Pardo, Angeles
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6650728/
https://ncbi.nlm.nih.gov/pubmed/31307975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019000019
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