Gene expression profile induced by arsenic trioxide in chronic lymphocytic leukemia cells reveals a central role for heme oxygenase-1 in apoptosis and regulation of matrix metalloproteinase-9

CLL remains an incurable disease in spite of the many new compounds being tested. Arsenic trioxide (ATO) induces apoptosis in all CLL cell types and could constitute an efficient therapy. To further explore this, we have studied the gene expression profile induced by ATO in CLL cells. ATO modulated...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Amigo-Jiménez, Irene, Bailón, Elvira, Aguilera-Montilla, Noemí, García-Marco, José A., García-Pardo, Angeles
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5347775/
https://ncbi.nlm.nih.gov/pubmed/27829220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13091
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