Brucella abortus Infection of Placental Trophoblasts Triggers Endoplasmic Reticulum Stress-Mediated Cell Death and Fetal Loss via Type IV Secretion System-Dependent Activation of CHOP

Subversion of endoplasmic reticulum (ER) function is a feature shared by multiple intracellular bacteria and viruses, and in many cases this disruption of cellular function activates pathways of the unfolded protein response (UPR). In the case of infection with Brucella abortus, the etiologic agent...

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Bibliografiske detaljer
Udgivet i:mBio
Main Authors: Byndloss, Mariana X., Tsai, April Y., Walker, Gregory T., Miller, Cheryl N., Young, Briana M., English, Bevin C., Seyffert, Núbia, Kerrinnes, Tobias, de Jong, Maarten F., Atluri, Vidya L., Winter, Maria G., Celli, Jean, Tsolis, Renée M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6650558/
https://ncbi.nlm.nih.gov/pubmed/31337727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01538-19
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