CD4(+) T Cell-derived IL-10 Promotes Brucella abortus Persistence via Modulation of Macrophage Function

Evasion of host immune responses is a prerequisite for chronic bacterial diseases; however, the underlying mechanisms are not fully understood. Here, we show that the persistent intracellular pathogen Brucella abortus prevents immune activation of macrophages by inducing CD4(+)CD25(+) T cells to pro...

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Detalhes bibliográficos
Main Authors: Xavier, Mariana N., Winter, Maria G., Spees, Alanna M., Nguyen, Kim, Atluri, Vidya L., Silva, Teane M. A., Bäumler, Andreas J., Müller, Werner, Santos, Renato L., Tsolis, Renée M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3688575/
https://ncbi.nlm.nih.gov/pubmed/23818855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003454
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