Brucella abortus Infection of Placental Trophoblasts Triggers Endoplasmic Reticulum Stress-Mediated Cell Death and Fetal Loss via Type IV Secretion System-Dependent Activation of CHOP

Subversion of endoplasmic reticulum (ER) function is a feature shared by multiple intracellular bacteria and viruses, and in many cases this disruption of cellular function activates pathways of the unfolded protein response (UPR). In the case of infection with Brucella abortus, the etiologic agent...

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發表在:mBio
Main Authors: Byndloss, Mariana X., Tsai, April Y., Walker, Gregory T., Miller, Cheryl N., Young, Briana M., English, Bevin C., Seyffert, Núbia, Kerrinnes, Tobias, de Jong, Maarten F., Atluri, Vidya L., Winter, Maria G., Celli, Jean, Tsolis, Renée M.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2019
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6650558/
https://ncbi.nlm.nih.gov/pubmed/31337727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01538-19
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