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Phospholipase A1 Modulates the Cell Envelope Phospholipid Content of Brucella melitensis, Contributing to Polymyxin Resistance and Pathogenicity

A subset of bacterial pathogens, including the zoonotic Brucella species, are highly resistant against polymyxin antibiotics. Bacterial polymyxin resistance has been attributed primarily to the modification of lipopolysaccharide; however, it is unknown what additional mechanisms mediate high-level r...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Kerrinnes, Tobias, Young, Briana M., Leon, Carlos, Roux, Christelle M., Tran, Lisa, Atluri, Vidya L., Winter, Maria G., Tsolis, Renée M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4604402/
https://ncbi.nlm.nih.gov/pubmed/26282427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00792-15
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