Scalable Synthesis of Biologically Relevant Spirocyclic Pyrrolidines

[Image: see text] Synthetic approaches toward multigram preparation of spirocyclic α,α-disubstituted pyrrolidines from readily available starting materials are discussed. It was shown that although a number of synthetic methodologies have been known to date, many of the title compounds remain hardly...

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Bibliografiske detaljer
Udgivet i:ACS Omega
Main Authors: Melnykov, Kostiantyn P., Artemenko, Artem N., Ivanenko, Bohdan O., Sokolenko, Yevhenii M., Nosik, Pavel S., Ostapchuk, Eugeniy N., Grygorenko, Oleksandr O., Volochnyuk, Dmitriy M., Ryabukhin, Sergey V.
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2019
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6648774/
https://ncbi.nlm.nih.gov/pubmed/31459845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.9b00896
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