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Effect of Charge Distribution in a Modified tRNA Substrate on Pre-Reaction Protein-tRNA Complex Geometry

[Image: see text] An important aspect of molecular mechanics simulations of a protein structure and ligand binding often involves the generation of reliable force fields for nonstandard residues and ligands. We consider the aminoacyl-tRNA synthetase (AaRS) system that involves nucleic acid and amino...

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Bibliografiske detaljer
Udgivet i:ACS Omega
Main Authors: Rayevsky, Alexey, Sharifi, Mohsen, Demianenko, Eugeniy, Volochnyuk, Dmitriy, Tukalo, Michael
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2021
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7906584/
https://ncbi.nlm.nih.gov/pubmed/33644545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.0c05143
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