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A modular and divergent approach to spirocyclic pyrrolidines
An efficient three-step sequence to afford a valuable class of spirocyclic pyrrolidines is reported. A reductive cleavage/Horner–Wadsworth–Emmons cascade facilitates the spirocyclisation of a range of isoxazolines bearing a distal β-ketophosphonate. The spirocyclisation precursors are elaborated in...
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| 出版年: | Chem Sci |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Royal Society of Chemistry
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8162384/ https://ncbi.nlm.nih.gov/pubmed/34094297 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0sc03676e |
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