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Third Generation Buchwald Precatalysts with XPhos and RuPhos: Multigram Scale Synthesis, Solvent-Dependent Isomerization of XPhos Pd G3 and Quality Control by (1)H- and (31)P-NMR Spectroscopy

The third generation Buchwald precatalysts Pd(ABP)(Phos)(OMs) (also known as Phos Pd G3)) with XPhos and RuPhos were prepared in multigram scale by a modified procedure (ABP = fragment of C-deprotonated 2-aminobiphenyl, XPhos = 2-dicyclohexylphosphino-2′,4′,6′-triisopropylbiphenyl, RuPhos = 2-dicycl...

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Publicat a:Molecules
Autors principals: Sotnik, Svitlana O., Mishchenko, Artem M., Rusanov, Eduard B., Kozytskiy, Andriy V., Gavrilenko, Konstantin S., Ryabukhin, Sergey V., Volochnyuk, Dmitriy M., Kolotilov, Sergey V.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8228727/
https://ncbi.nlm.nih.gov/pubmed/34207506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26123507
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