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Ligand Effects of BrettPhos and RuPhos on Rate-Limiting Steps in Buchwald–Hartwig Amination Reaction Due to the Modulation of Steric Hindrance and Electronic Structure

[Image: see text] The differences in catalytic activity between two catalyst ligands of Buchwald–Hartwig amination reaction, BrettPhos versus RuPhos, were investigated using density functional theory (DFT) calculations. The reaction process consists of three consecutive steps: (1) oxidative addition...

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Detalhes bibliográficos
Publicado no:ACS Omega
Main Authors: Tian, Jiaqi, Wang, Gaobo, Qi, Zheng-Hang, Ma, Jing
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2020
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7469115/
https://ncbi.nlm.nih.gov/pubmed/32905323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.0c01528
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