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Distinct immunocyte-promoting and adipocyte-generating stromal components coordinate adipose-tissue immune and metabolic tenors

Regulatory T cells (Tregs) are key brakes on the visceral adipose tissue (VAT) inflammation that regulates local and systemic metabolic tenor. Breakdown of this regulation promotes type 2 diabetes. The cytokine, IL-33, expands and sustains the unique Treg population residing within VAT. Here, relyin...

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Detalhes bibliográficos
Publicado no:Sci Immunol
Main Authors: Spallanzani, Raul German, Zemmour, David, Xiao, Tianli, Jayewickreme, Teshika, Li, Chaoran, Bryce, Paul J., Benoist, Christophe, Mathis, Diane
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6648660/
https://ncbi.nlm.nih.gov/pubmed/31053654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.aaw3658
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