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TCR transgenic mice reveal step-wise, multi-site acquisition of the distinctive fat-Treg phenotype

Visceral adipose tissue (VAT) hosts a population of regulatory T (Treg) cells, with a unique phenotype, that controls local and systemic inflammation and metabolism. Generation of a T-cell receptor transgenic mouse line, wherein VAT Tregs are highly enriched, facilitated study of their provenance, d...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Li, Chaoran, DiSpirito, Joanna, Zemmour, David, Spallanzani, Raul German, Kuswanto, Wilson, Benoist, Christophe, Mathis, Diane
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6046274/
https://ncbi.nlm.nih.gov/pubmed/29887374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.05.004
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