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Single-cell gene expression reveals a landscape of regulatory T cell phenotypes shaped by the TCR
CD4(+) T regulatory (T(reg)) cells are central to immune homeostasis, their phenotypic heterogeneity reflecting the diverse environments and target cells they regulate. To understand this heterogeneity, we combined single-cell RNAseq, activation reporter and TCR analysis to profile thousands of T(re...
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| Publicado no: | Nat Immunol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6069633/ https://ncbi.nlm.nih.gov/pubmed/29434354 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41590-018-0051-0 |
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