Remodeling and destabilization of chromosome 1 pericentromeric heterochromatin by SSX proteins

Rearrangement of the 1q12 pericentromeric heterochromatin and subsequent amplification of the 1q arm is commonly associated with cancer development and progression and may result from epigenetic deregulation. In many premalignant and malignant cells, loss of 1q12 satellite DNA methylation causes the...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Traynor, Sofie, Møllegaard, Niels Erik, Jørgensen, Mikkel G, Brückmann, Nadine H, Pedersen, Christina B, Terp, Mikkel G, Johansen, Simone, Dejardin, Jerome, Ditzel, Henrik J, Gjerstorff, Morten F
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Gene Regulation, Chromatin and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6648343/
https://ncbi.nlm.nih.gov/pubmed/31114908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz396
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados