Remodeling and destabilization of chromosome 1 pericentromeric heterochromatin by SSX proteins

Rearrangement of the 1q12 pericentromeric heterochromatin and subsequent amplification of the 1q arm is commonly associated with cancer development and progression and may result from epigenetic deregulation. In many premalignant and malignant cells, loss of 1q12 satellite DNA methylation causes the...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Autores principales: Traynor, Sofie, Møllegaard, Niels Erik, Jørgensen, Mikkel G, Brückmann, Nadine H, Pedersen, Christina B, Terp, Mikkel G, Johansen, Simone, Dejardin, Jerome, Ditzel, Henrik J, Gjerstorff, Morten F
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2019
Materias:
Gene Regulation, Chromatin and Epigenetics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6648343/
https://ncbi.nlm.nih.gov/pubmed/31114908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz396
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