Remodeling and destabilization of chromosome 1 pericentromeric heterochromatin by SSX proteins

Rearrangement of the 1q12 pericentromeric heterochromatin and subsequent amplification of the 1q arm is commonly associated with cancer development and progression and may result from epigenetic deregulation. In many premalignant and malignant cells, loss of 1q12 satellite DNA methylation causes the...

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Dettagli Bibliografici
Pubblicato in:Nucleic Acids Res
Autori principali: Traynor, Sofie, Møllegaard, Niels Erik, Jørgensen, Mikkel G, Brückmann, Nadine H, Pedersen, Christina B, Terp, Mikkel G, Johansen, Simone, Dejardin, Jerome, Ditzel, Henrik J, Gjerstorff, Morten F
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2019
Soggetti:
Gene Regulation, Chromatin and Epigenetics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6648343/
https://ncbi.nlm.nih.gov/pubmed/31114908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz396
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