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Ectopic expression of cancer/testis antigen SSX2 induces DNA damage and promotes genomic instability
SSX cancer/testis antigens are frequently expressed in melanoma tumors and represent attractive targets for immunotherapy, but their role in melanoma tumorigenesis has remained elusive. Here, we investigated the cellular effects of SSX2 expression. In A375 melanoma cells, SSX2 expression resulted in...
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Publicado no: | Mol Oncol |
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Main Authors: | , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
John Wiley and Sons Inc.
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5528659/ https://ncbi.nlm.nih.gov/pubmed/25363656 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2014.09.001 |
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