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Cysteine-rich granulin-3 rapidly promotes amyloid-β fibrils in both redox states
Granulins (GRNs 1–7) are cysteine-rich proteolytic products of progranulin (PGRN) that have recently been implicated in neurodegenerative diseases including frontotemporal dementia (FTD) and Alzheimer’s disease (AD). Their precise mechanism in these pathologies remains uncertain, but both inflammato...
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| Gepubliceerd in: | Biochem J |
|---|---|
| Hoofdauteurs: | , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2019
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6647844/ https://ncbi.nlm.nih.gov/pubmed/30782973 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20180916 |
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