Cysteine-rich granulin-3 rapidly promotes amyloid-β fibrils in both redox states

Granulins (GRNs 1–7) are cysteine-rich proteolytic products of progranulin (PGRN) that have recently been implicated in neurodegenerative diseases including frontotemporal dementia (FTD) and Alzheimer’s disease (AD). Their precise mechanism in these pathologies remains uncertain, but both inflammato...

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Detaylı Bibliyografya
Yayımlandı:Biochem J
Asıl Yazarlar: Bhopatkar, Anukool A., Ghag, Gaurav, Wolf, Lauren M., Dean, Dexter N., Moss, Melissa A., Rangachari, Vijayaraghavan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2019
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6647844/
https://ncbi.nlm.nih.gov/pubmed/30782973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20180916
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