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Sphingosine-coating of plastic surfaces prevents ventilator-associated pneumonia

ABSTRACT: Ventilator-associated pneumonia (VAP) is a major cause of morbidity and mortality in critically ill patients. Here, we employed the broad antibacterial effects of sphingosine to prevent VAP by developing a novel method of coating surfaces of endotracheal tubes with sphingosine and sphingos...

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Bibliographic Details
Published in:J Mol Med (Berl)
Main Authors: Seitz, Aaron P., Schumacher, Fabian, Baker, Jennifer, Soddemann, Matthias, Wilker, Barbara, Caldwell, Charles C., Gobble, Ryan M., Kamler, Markus, Becker, Katrin Anne, Beck, Sascha, Kleuser, Burkhard, Edwards, Michael J., Gulbins, Erich
Format: Artigo
Language:Inglês
Published: Springer Berlin Heidelberg 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6647234/
https://ncbi.nlm.nih.gov/pubmed/31222488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-019-01800-1
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