Neutrophils Kill Reactive Oxygen Species-Resistant Pseudomonas aeruginosa by Sphingosine

Background/Aims: Cystic fibrosis (CF) is dominated by chronic inflammation and infection of the lung resulting in lung destruction and early death of patients. The lungs of CF patients are characterized by a massive accumulation of neutrophils. It requires definition why these massive numbers of neu...

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Main Authors: Katrin Anne Becker, Xiang Li, Aaron Seitz, Joerg Steinmann, Anne Koch, Edward Schuchman, Markus Kamler, Michael J. Edwards, Charles C.  Caldwell, Erich Gulbins
Format: Artigo
Sprog:Inglês
Udgivet: Cell Physiol Biochem Press GmbH & Co KG 2017-10-01
Serier:Cellular Physiology and Biochemistry
Fag:
Reactive oxygen species
Sphingosine
Neutrophils
Pseudomonas aeruginosa
Pneumonia
Online adgang:https://www.karger.com/Article/FullText/482024
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