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Sphingosine kills bacteria by binding to cardiolipin

Sphingosine is a long-chain sphingoid base that has been shown to have bactericidal activity against many pathogens, including Pseudomonas aeruginosa, Staphylococcus aureus, and Escherichia coli. We have previously demonstrated that sphingosine is present in nasal, tracheal, and bronchial epithelial...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Verhaegh, Rabea, Becker, Katrin Anne, Edwards, Michael J., Gulbins, Erich
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7261797/
https://ncbi.nlm.nih.gov/pubmed/32327486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.012325
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