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Sphingosine-coating of plastic surfaces prevents ventilator-associated pneumonia

ABSTRACT: Ventilator-associated pneumonia (VAP) is a major cause of morbidity and mortality in critically ill patients. Here, we employed the broad antibacterial effects of sphingosine to prevent VAP by developing a novel method of coating surfaces of endotracheal tubes with sphingosine and sphingos...

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Detalhes bibliográficos
Publicado no:J Mol Med (Berl)
Main Authors: Seitz, Aaron P., Schumacher, Fabian, Baker, Jennifer, Soddemann, Matthias, Wilker, Barbara, Caldwell, Charles C., Gobble, Ryan M., Kamler, Markus, Becker, Katrin Anne, Beck, Sascha, Kleuser, Burkhard, Edwards, Michael J., Gulbins, Erich
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6647234/
https://ncbi.nlm.nih.gov/pubmed/31222488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-019-01800-1
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