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Identification of novel breakpoints for locus- and region-specific translocations in 293 cells by molecular cytogenetics before and after irradiation

The human kidney embryonic 293 cell line (293 cells) is extensively used in biomedical and pharmaceutical research. These cells exhibit a number of numerical and structural chromosomal anomalies. However, the breakpoints responsible for these structural chromosomal rearrangements have not been compr...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Binz, Regina L., Tian, Erming, Sadhukhan, Ratan, Zhou, Daohong, Hauer-Jensen, Martin, Pathak, Rupak
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6646394/
https://ncbi.nlm.nih.gov/pubmed/31332273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-47002-0
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