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Thrombomodulin Contributes to Gamma Tocotrienol-Mediated Lethality Protection and Hematopoietic Cell Recovery in Irradiated Mice

Systemic administration of recombinant thrombomodulin (TM) confers radiation protection partly by accelerating hematopoietic recovery. The uniquely potent radioprotector gamma tocotrienol (GT3), in addition to being a strong antioxidant, inhibits the enzyme hydroxy-methyl-glutaryl-coenzyme A reducta...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Pathak, Rupak, Shao, Lijian, Ghosh, Sanchita P., Zhou, Daohong, Boerma, Marjan, Weiler, Hartmut, Hauer-Jensen, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4393275/
https://ncbi.nlm.nih.gov/pubmed/25860286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0122511
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