Whole body proton irradiation causes acute damage to bone marrow hematopoietic progenitor and stem cells in mice

PURPOSE: Exposure to proton irradiation during missions in deep space can lead to bone marrow injury. The acute effects of proton irradiation on hematopoietic stem and progenitor cells remain undefined and thus were investigated. MATERIALS AND METHODS: We exposed male C57BL/6 mice to 0.5 and 1.0 Gy...

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Publicado en:Int J Radiat Biol
Autores principales: Chang, Jianhui, Wang, Yingying, Pathak, Rupak, Sridharan, Vijayalakshmi, Jones, Tamako, Mao, Xiao Wen, Nelson, Gregory, Boerma, Marjan, Hauer-Jensen, Martin, Zhou, Daohong, Shao, Lijian
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6693495/
https://ncbi.nlm.nih.gov/pubmed/28782442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/09553002.2017.1356941
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