Whole body proton irradiation causes acute damage to bone marrow hematopoietic progenitor and stem cells in mice

PURPOSE: Exposure to proton irradiation during missions in deep space can lead to bone marrow injury. The acute effects of proton irradiation on hematopoietic stem and progenitor cells remain undefined and thus were investigated. MATERIALS AND METHODS: We exposed male C57BL/6 mice to 0.5 and 1.0 Gy...

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Dettagli Bibliografici
Pubblicato in:Int J Radiat Biol
Autori principali: Chang, Jianhui, Wang, Yingying, Pathak, Rupak, Sridharan, Vijayalakshmi, Jones, Tamako, Mao, Xiao Wen, Nelson, Gregory, Boerma, Marjan, Hauer-Jensen, Martin, Zhou, Daohong, Shao, Lijian
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6693495/
https://ncbi.nlm.nih.gov/pubmed/28782442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/09553002.2017.1356941
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