Thrombomodulin Contributes to Gamma Tocotrienol-Mediated Lethality Protection and Hematopoietic Cell Recovery in Irradiated Mice

Systemic administration of recombinant thrombomodulin (TM) confers radiation protection partly by accelerating hematopoietic recovery. The uniquely potent radioprotector gamma tocotrienol (GT3), in addition to being a strong antioxidant, inhibits the enzyme hydroxy-methyl-glutaryl-coenzyme A reducta...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Pathak, Rupak, Shao, Lijian, Ghosh, Sanchita P., Zhou, Daohong, Boerma, Marjan, Weiler, Hartmut, Hauer-Jensen, Martin
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4393275/
https://ncbi.nlm.nih.gov/pubmed/25860286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0122511
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