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Detection of Inter-chromosomal Stable Aberrations by Multiple Fluorescence In Situ Hybridization (mFISH) and Spectral Karyotyping (SKY) in Irradiated Mice
Ionizing radiation (IR) induces numerous stable and unstable chromosomal aberrations. Unstable aberrations, where chromosome morphology is substantially compromised, can easily be identified by conventional chromosome staining techniques. However, detection of stable aberrations, which involve excha...
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| Published in: | J Vis Exp |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
MyJove Corporation
2017
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5352253/ https://ncbi.nlm.nih.gov/pubmed/28117817 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/55162 |
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