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Oridonin overcomes the gemcitabine resistant PANC-1/Gem cells by regulating GST pi and LRP/1 ERK/JNK signalling

Background: Chemotherapy remains a primary treatment method for advanced pancreatic cancer. However, chemotherapy resistance can influence the therapeutic effect of pancreatic cancer. The resistance mechanism of chemotherapeutic agents such as gemcitabine, which is an agent typically used to treat p...

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Vydáno v:Onco Targets Ther
Hlavní autoři: Wang, Bili, Shen, Can, Li, Yang, Zhang, Ting, Huang, Hui, Ren, Jun, Hu, Zhengjun, Xu, Jian, Xu, Bin
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6645696/
https://ncbi.nlm.nih.gov/pubmed/31410021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S208924
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