Oridonin overcomes the gemcitabine resistant PANC-1/Gem cells by regulating GST pi and LRP/1 ERK/JNK signalling

Background: Chemotherapy remains a primary treatment method for advanced pancreatic cancer. However, chemotherapy resistance can influence the therapeutic effect of pancreatic cancer. The resistance mechanism of chemotherapeutic agents such as gemcitabine, which is an agent typically used to treat p...

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Bibliografske podrobnosti
izdano v:Onco Targets Ther
Main Authors: Wang, Bili, Shen, Can, Li, Yang, Zhang, Ting, Huang, Hui, Ren, Jun, Hu, Zhengjun, Xu, Jian, Xu, Bin
Format: Artigo
Jezik:Inglês
Izdano: Dove 2019
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6645696/
https://ncbi.nlm.nih.gov/pubmed/31410021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S208924
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