HMGB1-mediated autophagy attenuates gemcitabine-induced apoptosis in bladder cancer cells involving JNK and ERK activation

High-mobility group box 1 (HMGB1) has been found to mediate autophagy during chemotherapy in several cancers. However, whether HMGB1plays a role in autophagy and chemoresistance in bladder cancer is elusive. In this report, HMGB1 expression was found to be increased in 30 primary bladder cancer tiss...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Yin, Hubin, Yang, Xiaoyu, Gu, Wen, Liu, Yan, Li, Xinyuan, Huang, Xiaolong, Zhu, Xin, Tao, Yong, Gou, Xin, He, Weiyang
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5641078/
https://ncbi.nlm.nih.gov/pubmed/29069735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17796
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