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Oridonin overcomes the gemcitabine resistant PANC-1/Gem cells by regulating GST pi and LRP/1 ERK/JNK signalling

Background: Chemotherapy remains a primary treatment method for advanced pancreatic cancer. However, chemotherapy resistance can influence the therapeutic effect of pancreatic cancer. The resistance mechanism of chemotherapeutic agents such as gemcitabine, which is an agent typically used to treat p...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Wang, Bili, Shen, Can, Li, Yang, Zhang, Ting, Huang, Hui, Ren, Jun, Hu, Zhengjun, Xu, Jian, Xu, Bin
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6645696/
https://ncbi.nlm.nih.gov/pubmed/31410021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S208924
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