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Non-covalent albumin-binding ligands for extending the circulating half-life of small biotherapeutics
Peptides and small protein scaffolds are gaining increasing interest as therapeutics. Similarly to full-length antibodies, they can bind a target with a high binding affinity and specificity while remaining small enough to diffuse into tissues. However, despite their numerous advantages, small bioth...
Guardat en:
| Publicat a: | Medchemcomm |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Royal Society of Chemistry
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6644573/ https://ncbi.nlm.nih.gov/pubmed/31391879 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9md00018f |
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