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Non-covalent albumin-binding ligands for extending the circulating half-life of small biotherapeutics

Peptides and small protein scaffolds are gaining increasing interest as therapeutics. Similarly to full-length antibodies, they can bind a target with a high binding affinity and specificity while remaining small enough to diffuse into tissues. However, despite their numerous advantages, small bioth...

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Detalhes bibliográficos
Publicado no:Medchemcomm
Main Authors: Zorzi, Alessandro, Linciano, Sara, Angelini, Alessandro
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6644573/
https://ncbi.nlm.nih.gov/pubmed/31391879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9md00018f
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