Negative Cooperative Binding of Thymidine, Ordered Substrate Binding, and Product Release of Human Mitochondrial Thymidine Kinase 2 Explain Its Complex Kinetic Properties and Physiological Functions

Lignende værker

• The Kinetic Effects on Thymidine Kinase 2 by Enzyme-Bound dTTP May Explain the Mitochondrial Side Effects of Antiviral Thymidine Analogs
  af: Wang, Liya, et al.
  Udgivet: (2011)
• Oxidative Stress Induced S-glutathionylation and Proteolytic Degradation of Mitochondrial Thymidine Kinase 2
  af: Sun, Ren, et al.
  Udgivet: (2012)
• Structural basis for ordered substrate binding and cooperativity in aspartate transcarbamoylase
  af: Wang, Jie, et al.
  Udgivet: (2005)
• Basic biochemical characterization of cytosolic enzymes in thymidine nucleotide synthesis in adult rat tissues: implications for tissue specific mitochondrial DNA depletion and deoxynucleoside-based therapy for TK2-deficiency
  af: Wang, Liya, et al.
  Udgivet: (2020)
• Nonpolar Nucleoside Mimics as Active Substrates for Human Thymidine Kinases
  af: Jarchow-Choy, Sarah K., et al.
  Udgivet: (2009)