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Single-Molecule Magnetic Tweezer Analysis of Topoisomerases
Magnetic tweezers (MT) provide a powerful single-molecule approach to study the mechanism of topoisomerases, giving the experimenter the ability to change and read out DNA topology in real time. By using diverse DNA substrates, one can study different aspects of topoisomerase function and arrive at...
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| Publié dans: | Methods Mol Biol |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6643975/ https://ncbi.nlm.nih.gov/pubmed/29177739 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-7459-7_10 |
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