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Single-Molecule Magnetic Tweezer Analysis of Topoisomerases

Magnetic tweezers (MT) provide a powerful single-molecule approach to study the mechanism of topoisomerases, giving the experimenter the ability to change and read out DNA topology in real time. By using diverse DNA substrates, one can study different aspects of topoisomerase function and arrive at...

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Detalles Bibliográficos
Publicado en:Methods Mol Biol
Main Authors: Gunn, Kathryn H., Marko, John F., Mondragón, Alfonso
Formato: Artigo
Idioma:Inglês
Publicado: 2018
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6643975/
https://ncbi.nlm.nih.gov/pubmed/29177739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-7459-7_10
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