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Multiple-attempt dynamics of type IA topoisomerases revealed in an orthogonal single-molecule experiment

Topoisomerases are enzymes involved in maintaining the topological state of cellular DNA. Despite many structural, biophysical, and biochemical studies, their dynamic characteristics remain poorly understood. Recent single molecule experiments revealed that an important feature of the type IA topois...

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Detalhes bibliográficos
Publicado no:Nat Struct Mol Biol
Main Authors: Gunn, Kathryn H., Marko, John F., Mondragón, Alfonso
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5516274/
https://ncbi.nlm.nih.gov/pubmed/28414321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3401
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