Profound Tissue Specificity in Proliferation Control Underlies Cancer Drivers and Aneuploidy Patterns

Genomics has provided a detailed structural description of the cancer genome. Identifying oncogenic drivers that work primarily through dosage changes is a current challenge. Unrestrained proliferation is a critical hallmark of cancer. We constructed modular, barcoded libraries of human open reading...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Cell
Main Authors: Sack, Laura Magill, Davoli, Teresa, Li, Mamie Z., Li, Yuyang, Xu, Qikai, Naxerova, Kamila, Wooten, Eric C., Bernardi, Ronald J., Martin, Timothy D., Chen, Ting, Leng, Yumei, Liang, Anthony C., Scorsone, Kathleen A., Westbrook, Thomas F., Wong, Kwok-Kin, Elledge, Stephen J.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6643283/
https://ncbi.nlm.nih.gov/pubmed/29576454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.02.037
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker