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A genetic interaction analysis identifies cancer drivers that modify EGFR dependency

A large number of cancer drivers have been identified through tumor sequencing efforts, but how they interact and the degree to which they can substitute for each other have not been systematically explored. To comprehensively investigate how cancer drivers genetically interact, we searched for modi...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Liao, Sida, Davoli, Teresa, Leng, Yumei, Li, Mamie Z., Xu, Qikai, Elledge, Stephen J.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5322732/
https://ncbi.nlm.nih.gov/pubmed/28167502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.291948.116
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