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STOP gene Phactr4 is a tumor suppressor

Cancer develops through genetic and epigenetic alterations that allow unrestrained proliferation and increased survival. Using a genetic RNAi screen, we previously identified hundreds of suppressors of tumorigenesis and/or proliferation (STOP) genes that restrain normal cell proliferation. Our STOP...

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Detalhes bibliográficos
Main Authors: Solimini, Nicole L., Liang, Anthony C., Xu, Chunxiao, Pavlova, Natalya N., Xu, Qikai, Davoli, Teresa, Li, Mamie Z., Wong, Kwok-Kin, Elledge, Stephen J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3562831/
https://ncbi.nlm.nih.gov/pubmed/23319639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1221385110
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