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Generation of Tβ4 knock-in Cashmere goat using CRISPR/Cas9

The cashmere goat breed is known to provide excellent quality cashmere. Here, we attempted to breed high-yielding cashmere goats by specifically inserting the Tβ4 gene into the goat CCR5 locus and provided an animal model for future research. We successfully obtained Tβ4 knock-in goat without any sc...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Int J Biol Sci
Hauptverfasser: Li, Xiaocong, Hao, Fei, Hu, Xiao, Wang, Hui, Dai, Bai, Wang, Xiao, Liang, Hao, Cang, Ming, Liu, Dongjun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ivyspring International Publisher 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6643211/
https://ncbi.nlm.nih.gov/pubmed/31360116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.34820
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