The antipsychotic agent flupentixol is a new PI3K inhibitor and potential anticancer drug for lung cancer

Background: The phosphatidylinositol 3-kinase (PI3K)/AKT signaling pathway is hyperactivated in lung cancer and regulates a broad range of cellular processes, including proliferation, survival, angiogenesis, and metastasis. Thus PI3K is considered a promising target for therapy. To date, PI3K inhibi...

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Bibliographische Detailangaben
Veröffentlicht in:Int J Biol Sci
Hauptverfasser: Dong, Chao, Chen, Yin, Li, Hongjian, Yang, Yi, Zhang, Hongtao, Ke, Kunbin, Shi, Xi-Nan, Liu, Xu, Li, Ling, Ma, Jing, Kung, Hsiang-Fu, Chen, Ceshi, Lin, Marie Chia-mi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ivyspring International Publisher 2019
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6643147/
https://ncbi.nlm.nih.gov/pubmed/31337981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.32625
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