Adapalene inhibits the activity of cyclin-dependent kinase 2 in colorectal carcinoma

Cyclin-dependent kinase 2 (CDK2) has been reported to be overexpressed in human colorectal cancer; it is responsible for the G1-to-S-phase transition in the cell cycle and its deregulation is a hallmark of cancer. The present study was the first to use idock, a free and open-source protein-ligand do...

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Publicado no:Mol Med Rep
Main Authors: SHI, XI-NAN, LI, HONGJIAN, YAO, HONG, LIU, XU, LI, LING, LEUNG, KWONG-SAK, KUNG, HSIANG-FU, LIN, MARIE CHIA-MI
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4626183/
https://ncbi.nlm.nih.gov/pubmed/26398439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2015.4310
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