Econazole nitrate inhibits PI3K activity and promotes apoptosis in lung cancer cells

The phosphatidylinositol-3-kinase (PI3K)/AKT signaling pathway plays a pivotal role in many cellular processes, including the proliferation, survival and differentiation of lung cancer cells. Thus, PI3K is a promising therapeutic target for lung cancer treatment. In this study, we applied free and o...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Dong, Chao, Yang, Runxiang, Li, Hongjian, Ke, Kunbin, Luo, Chunxiang, Yang, Fang, Shi, Xi-Nan, Zhu, Ying, Liu, Xu, Wong, Man-Hon, Lin, Guimiao, Wang, Xiaomei, Leung, Kwong-Sak, Kung, Hsiang-Fu, Chen, Ceshi, Lin, Marie Chia-mi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5740072/
https://ncbi.nlm.nih.gov/pubmed/29269744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-18178-0
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