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Liquid–liquid phase separation of tau protein: The crucial role of electrostatic interactions
Recent studies have indicated that tau, a protein involved in Alzheimer's disease and other neurodegenerative disorders, has a propensity to undergo liquid–liquid phase separation (LLPS). However, the mechanism of this process remains unknown. Here, we demonstrate that tau LLPS is largely drive...
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| Publicat a: | J Biol Chem |
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| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6643045/ https://ncbi.nlm.nih.gov/pubmed/31097543 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.AC119.009198 |
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