Protein painting, an optimized MS-based technique, reveals functionally relevant interfaces of the PD-1/PD-L1 complex and the YAP2/ZO-1 complex

Protein–protein interactions lie at the heart of many biological processes and therefore represent promising drug targets. Despite this opportunity, identification of protein–protein interfaces remains challenging. We have previously developed a method that relies on coating protein surfaces with sm...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Autores principales: Haymond, Amanda, Dey, Douglass, Carter, Rachel, Dailing, Angela, Nara, Vaishnavi, Nara, Pranavi, Venkatayogi, Sravani, Paige, Mikell, Liotta, Lance, Luchini, Alessandra
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2019
Materias:
Cell Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6643031/
https://ncbi.nlm.nih.gov/pubmed/31167787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.007310
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